Polymer microlenses for quantifying cell sheet mechanics
نویسندگان
چکیده
منابع مشابه
Polymer microlenses for quantifying cell sheet mechanics.
Mechanical interactions between individual cells and their substrate have been studied extensively over the past decade; however, understanding how these interactions change as cells interact with neighboring cells in the development of a cell sheet, or early stage tissue, is less developed. We use a recently developed experimental technique for quantifying the mechanics of confluent cell sheet...
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We report polymer capsule-based probes for quantifying the pressure exerted by cells during capsule internalisation (Pin). Poly(methacrylic acid) (PMA) capsules with tuneable mechanical properties were fabricated through layer-by-layer assembly. The Pin was quantified by correlating the cell-induced deformation with the ex situ osmotically induced deformation of the polymer capsules. Ultimately...
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ژورنال
عنوان ژورنال: Soft Matter
سال: 2010
ISSN: 1744-683X,1744-6848
DOI: 10.1039/b916385a